For those who are having trouble updating or installing your anti-spyware and anti-virus programs due to Antivirus 2009 and its ilk, here is the solution.

This particular virus was bundled with a hidden process named TDSSserv.sys It's a service that re-directs all software updates to 127.0.0.1 (your own computer) so that nothing will update. It also prevents Malwarebytes and Hijack This!(probably more) from installing or running.

What you need to do is go to Start, Control Panel, System, Hardware, Device Manager, Show Hidden Devices.

Scroll down to Non-plug and Play Drivers and click the plus icon to open those drivers.

Then search for TDSSserv.sys.

Right click on it, and select Disable.

Note If you select Uninstall, it will install itself again when you reboot the system, so DON'T select Uninstall.

Now people will be able to update and use their programs and delete the virus. I used Malware Bytes.

---------I just C/P from comments from somewhere on the interwebs, but it helped me once. I had the same problem trying to install malwarebytes, even after renaming the installer. This fix helped with that issue as well. This will allow Malwarebytes to be installed without changing the name, without being in safemode, without installing it 3 times. (Though you should run it from safe-mode anyway because it has an easier time deleting locked files). Also clear your temporary internet files/history/cookies, it will speed up your scans immensely.